Home > Medicine > Physiology > Volume-9 > Issue-2 > Role of Ethanolic Cabbage Extract on Blood Glucose Level and Liver Function of Alloxan Induced Diabetic of Male Wistar Rat

Role of Ethanolic Cabbage Extract on Blood Glucose Level and Liver Function of Alloxan Induced Diabetic of Male Wistar Rat

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Last date : 27-Oct-2025

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Role of Ethanolic Cabbage Extract on Blood Glucose Level and Liver Function of Alloxan Induced Diabetic of Male Wistar Rat


Okonkwo Chukwudi Onyeka John | Ezeokafor Emmanuel Nonso | Nwaefulu Kester Eluemunor



Okonkwo Chukwudi Onyeka John | Ezeokafor Emmanuel Nonso | Nwaefulu Kester Eluemunor "Role of Ethanolic Cabbage Extract on Blood Glucose Level and Liver Function of Alloxan Induced Diabetic of Male Wistar Rat" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-9 | Issue-2, April 2025, pp.1372-1384, URL: https://www.ijtsrd.com/papers/ijtsrd79830.pdf

Plants in folklore medicine has shown to posse’s antidiabetic and hepatoprotective tendencies, owing to the facts that most plant material contains phytochemical which can be therapeutically employed in the management of different pathological conditions. A total of 36 male wistar rat was used for this study, and the animal where divided into six groups of six animal, Group 1: (positive control): Normal rats received only feed and distilled water for three weeks. Group 2:(Negative control): Diabetic rats which received only feed and water. Group 3: In this group, diabetic rats were induced with 150mg/kg of alloxan and treated with low dose of extract (cabbage extract - 150mg/kg) for 3 weeks. Group 4: In this group, diabetic rats were induced with 150mg/kg of alloxan and treated with medium dose of extract (cabbage extract- 300mg/kg) for 3 weeks Group 5: In this group, diabetic rats were induced with 150mg/kg of alloxan and treated with high dose of extract (cabbage extract - 600mgkg).Group 6: In this group, normal rats received high dose of extract (cabbage extract - 600mg/kg) for two weeks before it was induced diabetes 150mg/kg. The results obtained from this study demonstrated that cabbage supplementation reduced the high blood sugar levels as observed in diabetic rats in this study. The present study also indicated a marked increase in the ALP levels which is suggesting an adverse effect of cabbage on the liver, therefore there is the need for more study on the toxicological profile of cabbage on the liver.

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IJTSRD79830
Volume-9 | Issue-2, April 2025
1372-1384
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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